Central San Mateo Vacations from $653

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Your Central San Mateo Vacation

Book a Central San Mateo vacation package and discover the way of life and vibe of this unique neighborhood. With all your travel plans taken care of, the only thing you need to concentrate on here is having an absolute ball. Some top nearby attractions to visit during your trip to Central San Mateo include Coyote Point Park, Hillsdale Shopping Center and Poplar Creek Golf Course. Expedia can help turn your ideal Central San Mateo vacation into reality, whatever your budget or travel plans.

The Latest Central San Mateo Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Fitzgerald Hotel

Fitzgerald Hotel

3 out of 5
Union Square
Price was $1,054, price is now $653 per person
$653
per person
Dec 27 - Jan 1
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to San Francisco (SFO)
7.8/10 Good! (447 reviews)
The hotel is easy access to all tourist spots

Reviewed on Oct 6, 2025

Aqua Breeze Inn

Aqua Breeze Inn

2.5 out of 5
Westside Santa Cruz
Price was $2,952, price is now $1,373 per person
$1,373
per person
Nov 27 - Dec 2
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Jose (SJC)
8/10 Very Good! (1,002 reviews)
AC was good! Loved the family style room

Reviewed on Sep 29, 2025

1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $2,630, price is now $1,515 per person
$1,515
per person
Dec 29 - Jan 2
found 1 hour ago
Roundtrip non-stop flight included
Atlanta (ATL) to San Francisco (SFO)
9.2/10 Wonderful! (450 reviews)
My favorite hotel in the city

Reviewed on Sep 24, 2025

Appellation Healdsburg

Appellation Healdsburg

4.5 out of 5
Save 100% on your flight
Price was $2,389, price is now $1,381 per person
$1,381
per person
Dec 12 - Dec 19
found 17 hours ago
Roundtrip flight included
Atlanta (ATL) to San Francisco (SFO)
9.8/10 Exceptional! (6 reviews)
What a great new property! Welcoming staff, very clean and fresh facilities. Bar staff could be friendlier and mire helpful. Valet, check in and restaurant staff very friendly.

Reviewed on Oct 5, 2025

Marbella Lane Tuscan Villa with Hot Tub

Marbella Lane Tuscan Villa with Hot Tub

3 out of 5
Rockaway Beach
Save 100% on your flight
Price was $1,385, price is now $865 per person
$865
per person
Dec 12 - Dec 15
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
9.6/10 Exceptional! (17 reviews)

Where to stay in Central San Mateo

Find the best Central San Mateo areas and neighborhoods for the activities you enjoy most. Learn more about Central San Mateo
Union Square which includes a high rise building and a city

Union Square

4/5(5,164 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Find hotels in Union Square

Central San Mateo Hotel Deals

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $140 total per night from Nov 2 to Nov 3
$140 total
Nov 2 - Nov 3
Total with taxes and fees
8.8/10 Excellent! (4,661 reviews)
"The view was great. I had the privledge to get the corner panoramic view room. Saw an amazing orange full moon. Has great coffee and treats downstairs. The hard boil eggs with salt and V8 juice with a water on my way out to Alcatraz was just the perfect light meal to go. Front desk was friendly. ..."

Reviewed on Oct 6, 2025

Holiday Inn Golden Gateway by IHG
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $133 total per night from Nov 2 to Nov 3
$133 total
Nov 2 - Nov 3
Total with taxes and fees
8.6/10 Excellent! (1,848 reviews)
"Clean and awesome"

Reviewed on Oct 6, 2025

Hilton San Francisco Financial District
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$153 nightly
The price is $180 total per night from Nov 5 to Nov 6
$180 total
Nov 5 - Nov 6
Total with taxes and fees
8.8/10 Excellent! (6,926 reviews)
"Overall great! The only slightly challenging elements were the lack of a fan to run low all night, along with the loud a/c unit, and the staff not knowing about where to access ev charge stations. The Bellman did know of a station that worked out. Otherwise, well-done! Excellent Breakfast ..."

Reviewed on Oct 5, 2025

Hotel Riu Plaza Fisherman's Wharf
See all 4,798 properties in Central San Mateo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Central San Mateo

Central Park

4/5(16 reviews)

Central Park is just one of the places to see in San Mateo, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Central Park

The San Mateo Japanese Garden

Enjoy an outing to The San Mateo Japanese Garden during your stay in San Mateo. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

The San Mateo Japanese Garden

Things to do

Filoli House & Garden

Filoli House & Garden

$34
per adult
100% of travellers recommend
Filoli House & Garden
The Golden Hour

2hr. SUNSET Sailing Experience on San Francisco Bay

$149
per adult
2hr. SUNSET Sailing Experience on San Francisco Bay
Inglenook and Sut,Napa Valley&Sausalito 1-Day Tou

Napa and Sonoma Small Group Wine Tour from San Francisco

$168
per traveler
Napa and Sonoma Small Group Wine Tour from San Francisco
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.